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Interactions between CD44ν and other oncologic pathways may promote recurrence in advanced cancer.
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Attempts have been made to define factors that might promote recurrence.
In addition, our analysis of recurrence type suggests that a high serum EGF concentration may increase the malignancy of tumor cells and may promote metastatic recurrence rather than multicentric occurrence.
I/R injury tends to disrupt normal liver tissues and create an environment that may promote tumor recurrence.
7 8 In addition, antibiotic treatment may cause an unfavourable shift towards colonisation with resistant pathogens, which are likely to promote recurrence of the infection.
Some have advocated that intralesional triamcinolone, surgical excision, and radiation actually promote recurrence [ 2, 10, 16].
Complex interactions among these signaling pathways may promote local invasion, distant metastasis, and recurrence of ampullary cancer rather than a single molecule, such as CD44s.
Bladder cancer is among the most prevalent malignancies, and is characterised by frequent tumour recurrences and localised inflammation, which may promote tissue invasion and metastasis.
Intravesical shedding of bladder tumor exosomes may promote the multifocality or progression of bladder lesions, thus implicating exosomes in the recurrence and progression of bladder cancer.
In ESCC, co-expression of both aFGF and FGFR1 was associated with larger tumor area and worse prognosis which suggests that the membrane receptor may promote proliferation of esophageal cancer cells in an angiogenesis-independent and autocrine manner and may contribute to rapid recurrence after esophageal resection [ 47].
This may promote misdiagnosis of this injury.
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