Sentence examples for may promote dysfunction from inspiring English sources

Moreover, because β-cells lack certain antioxidant enzymes that dispose of reactive oxygen species (ROS), increased ROS production may promote dysfunction and even apoptosis.

A procoagulant state resulting in microvascular thrombi may promote organ dysfunction in sepsis.

In turn, circulating LPS may promote hepatic dysfunction by increasing hepatic inflammation and fibrosis [ 87].

Thus, Bim expression may promote PC dysfunction under high glucose conditions.

Recent study had shown hyperglycemia-impaired PI3K/Akt signaling may promote EC dysfunction in diabetes [ 33].

It has been shown that impaired PI3K/AKT signaling due to hyperglycemia may promote endothelial dysfunction in diabetes [ 18].

It has been postulated that postprandial lipemia may promote vascular dysfunction via an oxidative stress pathway [ 17- 19].

A more recent study suggests that this EBNA1-driven ROS accumulation may promote telomere dysfunction, another known molecular signal for DDR activation (Kamranvar and Masucci, 2011).

Although this response to stress might be adaptative in the early stage, when sustained it may cause malnutrition and immunosuppression and may promote organ dysfunction [ 59] and death [ 60].

Controlled animal experiments demonstrate that ultrafine particulate matter (PM), a component of traffic-related air pollution, can translocate to the brain via the olfactory nerve or systemic circulation (Elder et al. 2006; Oberdörster et al. 2004; Peters et al. 2006), where it may promote CNS dysfunction.

Increased visceral adipose tissue may be associated with accumulation of perivascular fat, which can serve as a reservoir for activated effector T cells that promote dysfunction in both hypertension and psoriasis [1].