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Transplantation of mesenchymal stem cells (MSCs) may promote bone healing.
The strain fields observed along the bone implant interface may promote bone maintenance and ingrowth.
If IL-10-producing osteoblast-like cells are induced from patient somatic cells and transplanted back into the destructive bone lesion, such therapy may promote bone remodeling by the cooperative effects of IL-10 and osteoblasts.
Specifically, osteoblasts secrete TGFβ1 in a manner that depends on the specific bone characteristics [52], and that may promote bone resorption via increasing IL-11 secretion [11] [13], [31], [53], [54].
Some studies suggest that oestrogen replacement therapy may promote bone healing around titanium (Ti) implants in osteoporotic bone [ 17, 18].
The bisphosphonates are able to relieve pain from metastatic bone disease and, when given intravenously, may promote bone healing of lytic metastases.
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Cargill has developed many products with odd-sounding new ingredients, including Bone Appetit, a raspberry tea with soy isoflavones, which "may help promote bone health and may help relieve some of the symptoms of menopause", and comes in small pink cans designed for the mature lady's handbag.There's nothing new about health food.
3 4 TWEAK may also promote bone and cartilage destruction through inhibition of chondrogenesis and osteogenesis and promotion of osteoclastogenesis. 2 These data raise the possibility that TWEAK may contribute to chronic synovitis, a notion supported by the observation that TWEAK expression is dramatically elevated in the murine collagen-induced arthritis (CIA) model of arthritis.
In addition, bone formation was increased in the TM injected CatnbEx3/+; Col2a1-CreER embryos indicated by von Kossa staining (Fig. 4A), suggesting that Wnt/ β-catenin signaling in chondrocytes may also promote bone formation in the perichondrium non-cell autonomously.
In the inflammatory arthritides such as RA, TNF-α and IL-1 may therefore promote bone loss by amplifying RANKL effects.
Other previous studies have shown that LLLT may enhance the osteogenic potential of osteoblasts, and may promote metabolic bone activity and bone remodeling [40, 41].
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