Sentence examples for may promote abnormal from inspiring English sources

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Hence, chronic inhibition of COX-2 may promote abnormal 5-LO activity.

In contrast, enhanced peritoneal NK cell mediated IFN- γ was observed in women with severe endometriosis which may promote abnormal proliferation and angiogenesis of endometrial cells [ 16, 17].

Based on the in vitro studies described above, intranuclear IL-1α may promote abnormal proliferation and excessive collagen production by SSc fibroblasts, contributing to the extensive fibrosis that characterizes the final pathology of this disease (Kawaguchi et al., 2004; Abraham and Varga, 2005; Kawaguchi et al., 2006).

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In addition, enhanced IFN levels may increase endo-thelial cell apoptosis and promote abnormal vasculogenesis.

A better comprehension of the mechanisms involved in these processes may enable us to understand the molecular pathways that promote abnormal repair and cartilage degradation in OA.

Oxidant-mediated RPE damage might promote abnormal angiogenesis [40].

The findings suggest that complex changes in the MMP-TIMP balance and altered MMP activity in aqueous humor may promote not only abnormal matrix remodeling characteristic of POAG but also RGC apoptosis which may be causally involved in the pathogenesis of POAG.

HCV proteins can interact with tumour suppressor proteins as well as with proteins involved in cell-cycle control, and these interactions may promote the development of abnormal cells in the liver.

In more advanced lesions, stromal dissolution may permit tumor spread and in highly malignant lesions an abnormal stroma may promote neoplasm progression.

When folate concentration is limited, the precursor pool of deoxynucleotide triphosphates is reduced, and misincorporation of uracil increases in "a catastrophic repair cycle" which may promote double-strand breaks, chromosomal damage, and abnormal cell growth (Fig. 1) (Reidy 1988; Blount and Ames 1994).

Abnormal ubiquitination of ANXA2 may promote the metastasis and infiltration of breast cancer cells by inducing high levels of ANXA2 expression [ 47].

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