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Partial ipsilateral cranial neuropathies may progress over several months.
Children with SOD should have regular endocrinology follow-up as hormonal insufficiencies may progress over time.
The instability may progress over time, especially if the C1 C2 region is stabilised surgically (Fig. 6) [5].
The disease is insidious and subclinical but may progress over decades into end-stage liver disease and hepatocellular carcinoma, which makes HCV cirrhosis a leading indication for orthotopic liver transplantation.
The recent finding that these injuries, like those of headache-free patients, may progress over time raises some doubts about their benign nature: among 26 subjects with WMHs, 8 patients had indeed new lesions after a follow-up of a mean duration of 33.2 months [71].
Thoracolumbar disc extrusions in chondrodystrophic dogs (Hansen type I protrusions) may progress over several days and are therefore not necessarily completed the day they are diagnosed.
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These results demonstrate that in the absence of gene flow local adaptation may progress significantly over less than a 20-generation time span.
The natural history of NAFLD shows that histopathological progression occurs in 32-37% of patients over 3-6 yeand and up to 12% of patients may progress to cirrhosis over 8-10 years [ 4].
To confirm the faulty S phase prior to G2/M, we increased the time between IdU and BrdU pulses to 2.5 hr to observe if the IdU+BrdU− cells in the basal S phase zone of the mutant may progress to mitosis over time.
However, the data from these 2 small studies show that even with surveillance and treatment, on average 9-13% AIN 3 may progress to invasive disease over 5 10 years, comparable to that observed for progression of CIN 3 over similar time periods.
Depending on the location and cell type, brain cancers may progress rapidly or slowly over a period of many years.
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