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Rarely, this may progress and the virus may invade the central nervous system, provoking a local inflammatory response.
Supposedly even in very early stages of RRMS a "clinical silent" focal or diffuse "background inflammation" not detectable in conventional MRI may progress and cause diffuse axonal damage.
If left untreated, this may progress and lead to a stiff deformity.
Although most cases can be managed pharmacologically and/or surgically, HF may progress and become unresponsive to conventional treatment [ 4].
The drawback of neoadjuvant chemotherapy is that patients who do not respond may progress and eventually become unresectable.
Furthermore, CRP and the ESR remain normal in a proportion of RA patients that may progress – and thus additional and more sensitive predictors are required.
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Scientific and technological advances may progress rapidly and boldly, but political support and competing priorities are thick with complexity and change slowly, challenging science-based conservation plans.
Overall, the combination of higher plasma glucose and insulin use may progress atherosclerosis and subsequently increase the risk of IHD among elderly diabetic individuals.
It may progress posteriorly and lead to pre-retinal neovascularization and secondary vasoproliferative complications [1, 2].
Protection devices may progress considerably and allow further radiation exposure reduction, notably of the extremities.
Their metabolic abnormalities may progress rapidly and fulfill the MetS definition within a year of follow-up.
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