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It has been proposed that maternal undernutrition may "programme" long-term changes in gene expression in the fetus, resulting in cardiovascular and metabolic abnormalities in later life.
Experimental models suggest that protein deficit in utero may programme abnormal glucose homeostasis and vascular endothelial dysfunction, whereas results are less consistent with regard to programming of high blood pressure [35], [43].
Early life may programme individuals to behave adaptively in a changing environment.
We have hypothesized that early exposures to geohelminths may programme the infant immune system for reduced allergy [ 39].
We have previously observed that, in this community, birth season predicts infection-related mortality, providing evidence that seasonal factors in early life may programme immune development [ 6, 7].
Severe stress during prenatal life may programme future health in future life, which highlights the importance of better care in women's health during pregnancy.
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Otherwise, this may hamper programme activities.
They may oversee programmes to get people back to work.
Teach the teachers programmes may assist in reducing variability between programmes and countries, and are probably underused in radiology.
The disclosure programme may be harsh and inequitable, but for healthier, acquisitive outfits it may have a silver lining.
Any means-tested programme may discourage work.
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