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These complications include bone pain, fractures, hypercalcemia and spinal cord compression, all of which may profoundly impair a patient's quality of life.
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Particularly, the elderly and those who suffer from visual disorders may be profoundly impaired by the low intensity, high dynamic range (HDR), and rapidly changing illumination conditions we often experience in our daily live as it is stated by Irawan et al. [1].
The commonest organism found, M. salivarium, is able to profoundly impair the functions of key immune cells and thus suggests that Mycoplasmataceae may contribute to VAP pathogenesis.
However, the viral immune evasion genes profoundly impair recognition of infected cells by CD8+ T cells.
We find that mutations associated with INAD and NBIA profoundly impair enzyme function in both phospholipase and lysophospholipase assays.
However, it contains three immune evasion genes that impact the MHC class I pathway and profoundly impair CD8+ T cell recognition of infected cells [9].
Antitermination activity would profoundly impair protein synthesis.
If not recognized or treated, depression can profoundly impair workers' quality of life [ 12].
As thiol antioxidants seem to be able to profoundly impair induced autophagy, we examined whether they could impair autophagy induced by mTOR inhibition and basal autophagy.
Mild hypothermia with core temperatures between 33°C and 34°C is relatively easy to induce during general anaesthesia because anaesthetics profoundly impair thermoregulatory responses [ 9- 12].
Despite the challenges, even profoundly impaired individuals, may achieve a profound emotional connection.
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