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While further studies should be certainly conducted to increase our understanding on the dose-response of HS, molecular findings suggest that the biochemical response to humic treatments may principally depend on a transcriptional mechanism of regulation, as previously hypothesized for the regulation of a maize isoform of H+-ATPase [34] and with a more holistic approach by Trevisan et al. [46].
Preclinical data suggest that this may principally apply to sequential signal detection, a core process of sustained attention.
In familial diseases, amyloid fibril aggregation may principally determine serious pathologies, including systemic and central neuropathies and cardiomyopathies leading to severe, life-threatening conditions [20].
Therefore, our findings concerning the patterns of vocal signaling allows us to hypothesize that eagle owls may principally vocalize at twilight because this timing of signaling maximizes the visual contrast of the white feathers associated with their vocal displays.
Since these problems occurred mainly in individuals at the lower end of the observed BMI variation and since low UCP levels seem less of a problem in studies of great apes which have larger bodies than macaques (e.g. [37]), body mass may principally be a critical parameter limiting the use of UCPs as biomarker.
The latter cases may principally occur in the case of chronically infected dogs or atypical presentations.
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Ruling out increases in the three most important sources of government income may be principally designed to put Labour on the spot.
Although many authorities have long noted the defensive and thermoregulatory functions of these structures, the plates, and the spikes, they may have principally served as indicators that allowed different species of stegosaurs to recognize each other.
And yet, as Phillip Sharp, the American winner of the 1993 prize for medicine, said of the historic house he bought with his prize, a Nobel prize may be principally about honour, but "the money is a nice part of the process".
The results of structural analysis of the catalysts for oxidative coupling of methane show that the promoting effects of the fluoride in the catalysts may be principally related to the phase phase interaction between fluoride and oxide.
In conclusion, even seemingly similar phenotypes in differential signaling may represent principally different mechanisms of G protein-uncoupling, which again are most likely caused by distinct conformational states.
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