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The organization and geometry of viable parameter spaces may prevent identification of a single best model improvement.
Of note, low tumor cell content may prevent identification of the BRAF V600E mutation by molecular analysis and result in false-negative results, but this limitation has been shown to be overcome by the use of BRAF V600E monoclonal antibody [ 18, 29, 30, 32, 34].
However, the specification of the background model structure is a potential limitation to the general use of the MDSFR technique, as the extracted scattering information is not allowed to deviate from the specified functionality; this constraint may prevent identification of subtle wavelength-dependent influences of scattering on the reflectance signal.
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Insufficient, improper, or inadequate sampling may delay or prevent identification of a causative agent.
These weather effects on the two measurements may prevent precise identification of eruption styles.
The lack of a single cell type underlying the development of a disease may prevent the identification of cell types associated with the disease.
Furthermore, the spread of genetic variants with small effect sizes across multiple genes may prevent the identification of disease-manifesting cell types.
Beyond laboratory-confirmed cases, an unknown burden of unconfirmed cases exists, since some persons do not present for care or receive a lumbar puncture, others have received pretreatment with antibiotics, and laboratory limitations may prevent etiologic identification.
The small number of cases leads to a relative lack of power, which may prevent the identification of true Tourette syndrome/chronic tic disorder risk factors that are uncommon in the study population (e.g. twin or premature births).
3 Despite high rates of postoperative satisfaction in patients, 4 their use has been restricted by concerns from ophthalmologists that an inability to visualise the retina may prevent the identification of life-threatening pathology principally uveal melanoma behind the occlusive IOL. 5 Morcher black IOLs have been demonstrated to transmit high levels of NIR light.
It is possible that different sequences with redundant activities reside in the elements, or alternatively, common elements may be sufficiently variable to prevent identification.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com