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However, it has been shown that for many dimensions the so-called curse of dimensionality may prevent effective cluster analysis, as the similarity measure may become less discriminant [3, 4].
Both animal and human studies demonstrate that Treg cell numbers are elevated in the acute stage of virus infection and could dampen the virus-specific adaptive T-cell response, which may prevent effective virus clearance [8] [11].
High/raised levels of aromatase may prevent effective blockade by inhibitors.
Change-makers should consider that multiple intertwined causes may prevent effective implementation.
It has previously been proposed that the tumour stroma may prevent effective tumour infiltration by immune cells (Ueno et al, 2004).
As well as being a direct cause of quadriceps muscle weakness, AMI may prevent effective muscle strengthening [ 8, 9], leading to long-term quadriceps muscle atrophy and weakness that is difficult to reverse.
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The virulence of the pathogen may also prevent effective innate and acquired responses from eliminating microorganisms before infection ensues.
Nevertheless, while defining the theoretically optimal level of component variety, there are other elements, more related to operators' attitude or to operative conditions, which may intervene and prevent effective exploitation of the existing variety.
Non-visualization of the pylorus secondary to gastric air, or a posterior position from gastric distention may prevent an effective evaluation.
This raises the question of what mechanisms may be operating to prevent effective implementation of the host immune responses to growing malignancies.
Invasions of privacy may create civil liability and prevent effective investigations of criminal misconduct.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com