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There is an increasing body of evidence that ED is the first sign of CVD in men with free medical history and may present well before CVD with a mean time-interval of even 3 years (Montorsi et al 2003).
Additionally, the convergence of these findings suggest that extra diligence be taken with "young adults" as pediatric-type GIST may present well beyond adolescence, particularly as these distinct sub-types have different causes, and consequently respond differently to treatments.
Additionally, these findings suggest that extra diligence be taken with "young adults" (aged 18-35 at diagnosis) as pediatric-type GIST may present well beyond adolescence, particularly as these distinct sub-types have different causes, and consequently respond differently to treatments.
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It was already described that this family of tumours, when originating from extraskeletal sites, occur in relatively older patients and may present as well-circumscribed, non-calcified masses, without the involvement of bone marrow (the hallmark of an osseous origin) [21].
New opportunities may present themselves as well.
Advanced cases of Paget's disease may present with a well-demarcated round or ovoid eczema-like plaque that is easily distinguished from the surrounding normal skin.
In its focal form, AIP may present with a well-defined focal mass-like lesion (Fig. 2b, c), causing irregular narrowing of the pancreatic duct, common bile duct (CBD) involvement and pancreatic tail retraction, in a manner that may mimic focal pancreatic cancer.
Less often patients may present with urticaria as well as subcutaneous nodules [ 3, 4].
With respect to this last aspect, it should be added that administrative data flows may present missing data as well as mistakes which may not be controlled.
In fact, there are reports demonstrating that transgenic plants carrying genes coding for osmoprotectants under a constitutive promoter may present morphological changes as well as growth rate and seed grain yield reduction [ 32, 33].
Moreover, these studies usually fail to point out the cases in which the proposed classifier may present significant gain over well-established classifiers.
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CEO of Professional Science Editing for Scientists @ prosciediting.com