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Silicone granulomas may present distant from the implant site; primarily, the ipsilateral chest wall and axillary lymph nodes are involved.
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These are highly aggressive and infiltrative tumours, may present with distant metastases and demonstrate high recurrence rate.
The presence of MVs in plasma has been used to explain why cancer patients may present a thromboembolic event distant from the location of tumour development.
PD related systemic complications may present as a periopathogenic bacteremia and subsequent distant (focal) infections; as periopathogenic toxemia or as a systemic immune mediated reaction induced by the localized periodontal inflammatory lesion [ 7].
Patients with NETs may present with local tumours, with or without regional or distant metastases.
Since then, some authors have suggested that a strict definition of primary extranodal lymphoma, which excluded patients with distant disease from the primary extranodal site, may present an incomplete picture of extranodal lymphoma [ 3- 5].
Early detection and treatment of recurrent disease are important as it may still present without distant metastases.
Going much further back in time - some 74,000 years - the most cataclysmic volcanic blast known, which made a crater 100km across at Toba in northern Sumatra, is charged with plunging the planet into a "volcanic winter", which according to some, may have presented our distant ancestors with a battle for survival.
Well, if I told you about that, I would have to present more distant mountains there.
This suggests that disseminated tumor cells from the mammary tissue may be present at distant organs at an early stage of tumor progression and remain dormant.
Disseminated breast cancer cells may be present at distant sites at the time of primary diagnosis of breast cancer in patients that exhibit no outward signs of clinical metastasis [ 18, 19].
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