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Individuals heterozygous for a single centric fusion may present diminished reproductive capacity, even though the trivalent structures formed segregate normally during meiosis [ 17].
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Similar to previous reports of prolonged BP recovery to laboratory mental stress characteristic of rumination [ 26, 31, 32], the tendency for relatively blunted BP dipping among high trait ruminators in the present study may represent diminished recovery from daily stress during nighttime sleep.
Both methods presented diminish the bacterial attachment and biofilm formation.
This connection may present a signalling pathway by which PrPC is required for intact Rab signalling, facilitating release, which will subsequently be diminished in prion disease resulting in synaptic dysfunction.
Animals that are heterozygous for chromosome rearrangements may present anomalous pairings during meiosis, which results in failure during gametogenesis and unbalanced gamete production, both of which cause diminished fertility or even sterility in the organism [ 15].
For instance HIV-associated neurocognitive disorders may present with varying degrees of motor impairment (such as tremor, impaired movement and problems associated with speech) and a progressive decline in cognition (diminished memory function and difficulty associated with concentration) [ 3].
Diminished activation is in agreement with the well-established fact that clinical diagnosis of PD can be made from Braak stage 3 onwards, although patients may present prodromal signs in early stages [ 119, 121].
The wires may present a safety hazard.
A low ankle-arm index (AAI) is a good marker of vascular events and may be diminished without presenting symptomatology (silent peripheral arterial disease).
However, some degree of contamination might be present and may have diminished the difference between both groups.
Given that functional POMC is mechanistically required for 5-HT pharmacotherapy appetite suppression, recent reports revealing perturbed POMC function and melanocortin system remodeling in middle-age presented the possibility that 5-HT compound anorectic efficacy may be diminished with age.
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