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Protein loss and high blood pressure, as well as the features on biopsy of the kidney if performed, may predict progression to advanced kidney disease.
This also underscores the need for biomarkers which not only may predict progression but may contribute to discovery of molecular mechanisms that are involved in disease pathogenesis.
One study has shown that urinary CTX-II may predict progression of structural damage in AS, as also documented for RA [ 127].
Thus, immunohistochemistry for not only MUC6 but also for αGlcNAc may predict progression and prognosis of patients with these types of tumors.
6 The serum titer of autoantibodies to oxidized LDL (oxLDL) has been shown to be associated with and may predict progression of atherosclerosis, 7 myocardial infarction, and coronary artery disease.
Elevated Ki-67 expression may predict progression to cancer in some precursor lesions (Shaaban et al, 2002); in DCIS, high Ki-67 expression levels may predict in situ or invasive recurrence (Simpson et al, 2007).
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Therefore, these data suggest that the use of a defined set of markers may accurately predict progression.
However, when acute phase reactants (APRs) are discordant, with elevation of only one (ESR or CRP), these laboratory test results may not predict progression of structural damage to joints [ 12].
In some populations (for example, immunoglobulin A nephropathy and ANCA vasculitis), renal biopsy allows disease classification that may predict CKD progression and response to therapy.
Collectively, our data prove that the reduced expression of miR-134 may predict aggressive progression and poor prognosis in human gliomas.
Consistent with the fear-avoidance model of chronic pain, greater pain-related fear has consistently been associated with more severe disability and may predict the progression of disability over time.
More suggestions(15)
may predict mortality
may retard progression
may predict outcome
may influence progression
may prevent progression
may allow progression
may reflect progression
may avoid progression
may regulate progression
may predict disease
may predict risk
may predict infidelity
may predict need
may forestall progression
may mediate progression
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