Mutations in X-linked microRNAs that can possibly predispose males to schizophrenia were identified.
The identification of age-modified CpG sites during early childhood is also important, because early exposure to environmental factors such as pollutants and pesticides might alter the methylation levels of inflammatory genes and these signatures may be sustained during years, possibly predisposing to disease [ 30, 31].
We assume that this duplication does not have the strong pathogenic effect of the previously reported deletions within this region and may be a population-specific variant, possibly predisposing to ASD under certain conditions.
The increased rate of OASIS among women undergoing VBAC may be explained by fetopelvic disproportion leading to a primary caesarean section possibly predisposing to OASIS at first vaginal delivery [ 25, 38].
In addition to possibly predisposing elderly individuals to cancer or autoimmune/inflammatory conditions (discussed earlier), increased basal states of inflammation may also hamper the development or resolution of immune responses to pathogens.
Ho and others argue (cited in Straub et al., 1997) that low individualism (collectivistic culture) possibly predisposes a culture against CMCs, because these media mute the group effect.
If so, this possibly predisposes these patients for vascular disorders later in life.
In conclusion, whole-genome sequencing identified a mutation in RBCK1 as possibly predisposing to a novel, extremely rare Mendelian disease.
Juárez may, possibly, be turning a corner.
