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While humans lack the homologous genes, the p65 GTPases to which hGBPs belong may possess functions similar to the murine p47 GTPases.
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The results of changing immunoreactivity during the lamprey life cycle suggest that lamprey adenohypophysial hormones, ACTH, MSH, GH and GTH, may possess biological functions similar to those of more advanced gnathostome vertebrates.
While compound knockout of jnk1 and jnk2 is embryonic lethal, single knockouts are viable, suggesting that jnk1 and jnk2 may possess redundant functions during development.
It is known that PS1 and PS2 have distinct expression patterns [62] and thus we speculate that the two proteins may possess distinct functions.
However, we cannot rule out the possibility that RP-associated splicing factors may possess unknown functions required only for processing some retina-specific transcripts and thus, a decrease in their expression or in their function due to genetic mutations may lead to RP.
In addition, many mRNAs include longer 5' leader regions which may possess regulatory functions.
Recent evidence suggests that glycogen levels may possess important functions beyond controlling whole body metabolism.
Therefore, ECPsp may possess dual functions involving both protein secretion and the regulation of gene expression.
Thus, it has been hypothesized that miRNAs in the miR-17 ~ 92 family may possess related functions [ 32].
Some mycoplasma paralog proteins, such as lipoate- protein ligase may possess different functions or differ in substrate specificity.
It is of note that HID1 homologs are found in many plant species [86] and may possess conserved functions in different species.
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