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In auditor speak, GAO says that "[b]ecause EPA had not developed sufficient chemical assessment information under these programs to limit exposure to many chemicals that may pose substantial health risks, we added this issue to the High Risk List in 2009".
Among the large number of stressors temperature is considered a particularly important one, because variable thermal environments are common and may pose substantial challenges for individual survival and reproduction [4] [8].
Although it is not conceptually difficult to model the process of biological speciation as a phylogenetic tree, graphically the exercise may pose substantial challenges.
For organizations with extensive existing software systems, introducing an additional data management system may pose substantial challenges in integration, interoperability, data redundancy and data exchange.
One out of 12 patients (8.3%) presented with abnormalities of all three lipid values, LDL-C, HDL-C and TG, which may pose substantial therapeutic challenges to the physician.
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Thus, their substantial extent may pose significant effects on the post-treatment quality of life of many of the patients (Iqbal and Kim 2008; Doyle et al. 2006; Hannahan and Eleazer 2008).
Second, the absence of non-trivial timing signatures for significant parts of both datasets may pose a substantial problem if data is used for detailed timing (or causal) analysis.
For example, the Environmental Protection Agency's Toxic Substances Control Act, enacted in 1976, already requires manufacturers to report any products that employ a substance that is not on the EPA's list of approved substances; and even if a substance is on the list, the TSCA requires reports of any product that may pose a "substantial risk" in the particular form in which it is being used.
Our results show that contagious caprine pleuropneumonia may pose a substantial threat to the survival of endangered Tibetan antelope.
Less emphasis has been placed on brief peaks in suspended particulate levels, which may pose a substantial nuisance, irritant, or health hazard.
For most immunocompetent patients, colonization with vancomycin-resistant enterococci (VRE) does not present a significant personal health risk; however, these patients may function as carriers, and following hospital admission, may pose a substantial risk for transmission [ 1- 4].
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CEO of Professional Science Editing for Scientists @ prosciediting.com