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Overexpressing mutant human transgenes in mice may poorly model the disorder or disorders that characterize the vast majority of AD patients.
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There is also a need for a broader assessment of the value of self-management in the context of wider service redesign, as many models in this area highlight the interrelationships between patients, professionals, and the wider service context [ 13, 44], which may be poorly modelled by conventional trials.
However, recently introduced examples show that this may not always be true, as the reduced stochastic model may poorly approximate the full model even when their deterministic counterparts agree [ 27, 30, 35, 36].
It is, arguably, even more poorly modelled.
In CHT knockout mice, however, loss of CHT expression occurs throughout life, irrespective of demand, and thus the model may poorly represent the therapeutic limitations associated with CHT antagonism.
Therefore, genome alignments may poorly align these regions across species.
This model may fit poorly, especially when a nonsymmetric response is available.
This model may be poorly structured and unsupported in the context of patients with chronic illness who can require multiple presentations across private medical specialists, community health, general practice, allied health, and hospital inpatient and outpatient clinics.
Prediction models may perform poorly in a new setting.
This was important because close conformance to the training data by overfitted models (i.e. fitting error variation) may cause models to perform poorly when projected to other areas or climate datasets.
However, they stop short at examining the impact of decreasing video frame rate; their scheme may generalize poorly in such cases since it models the consecutive changes in video.
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