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Since RIP140 also can bind to and repress many of these transcription factors, including PPARα, PPARγ and ERRα [21,39] it appears that the PGC1α and RIP140 coregulators may play mutually opposing roles in controlling sets of metabolic genes.
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These interested parties play mutually reinforcing roles in sustaining the fiction that continuous profit growth is either possible or desirable.
There has been previous speculation that regions with potential for competing, mutually exclusive hairpins may play a role in regulating transcription and/or replication [e.g. ref. [ 7]].
Behavioral interventions and exogenous insulin administration are not mutually exclusive, and both may play important roles in preventing NODAT.
In the meantime, we note that both the TLR4 and opioid receptor mechanisms may play a role in LDN action, as the hypotheses are not mutually exclusive.
The calculations show that in the composites MgH2/NaAlH4 and MgH2/Na3AlH6, the components spontaneously destabilize mutually in specific relative amounts by forming NaMgH3, which may play only a catalytic role on the decomposition of (MgH2 + Al) mixture, NaAlH4, or Na3AlH6.
Although, the results were not statistically significant, probably due to the small number of cells evaluated, this suggests that mutually exclusive BRG1 and MYC mutations can be extended to other tumour types and that BRG1 may play an important role in neuroblastomas that are negative for MYC amplification.
All may play a part.
History may play a part.
It is important to note that the genes that fall into each of these classes are not mutually exclusive: genes involved in the metabolism of xenobiotic compounds could play the role of any of these multistep events, while other genes may play a greater role in one step than others.
Rod Stewart's "Maggie May" played.
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