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"We may play double-dummy bridge.
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This imaginative choice did not generate a trump trick, but it defeated the contract when declarer failed to play double-dummy.
And declarer, if playing double-dummy, would have overtaken her spade queen with dummy's king at Trick 4. The curious may work out the various possibilities.
But South was not playing double-dummy.
Playing double-dummy (seeing all of the cards), South would have won with his ace, played a spade to dummy's queen and led a low spade to bring down West's ace.
The only way to make the contract at this point, assuming everyone is playing double-dummy, is to call for the spade king to pin East's queen.
It takes an immediate club lead to defeat this contract if each side plays double-dummy (knowing where every card lies).
In addition to making patient recruitment harder, patient selection bias may occur in double-dummy trials as investigators may doubt the ability of elderly or frail patients to follow complex instructions [ 32].
Just playing doubles?
Try playing doubles.
Playing doubles is more dangerous.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com