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For example, the authors also confess that one system already in place as a result of attention to medical error, the reduction of work hours for physicians in training, may paradoxically increase the problem of mistakes -- at least temporarily.
"Criminalization is not an effective strategy for reducing transmission of infectious diseases and in fact may paradoxically increase infectious disease transmission," they said in a March statement.
Furthermore, pre-treatment of the stroma with anti-angiogenesis molecules prior to tumour implantation in mouse tumour models may paradoxically increase tumour development [6], [7].
Namely, the gradual recruitment of deeper signal sources (having more active membrane but which are relatively shielded at first), may paradoxically increase the functional signal, without causing a proportional increase in resting light intensity.
Although our observations may correspond to reports in humans that fluoxetine treatment in adolescents may paradoxically increase depression-related behavior without notification of gender differences [4]; [7], future research is needed to elucidate the age-dependent effects of SSRIs in depression-related animal models as a function of sex.
Wild-type IGFBP4 may paradoxically increase tumour growth by serving as a reservoir of IGF1.
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This is exemplified by the results of the recent STEP trial, which showed that a HIV-1 vaccine that conferred protection in non-human primates not only failed to confer protection in humans, but may have paradoxically increased risk of transmission [3], [4], [5], [6].
Conversely, there is speculation that the modern helmet may have paradoxically increased the risk of concussion because of the large size and weight of the helmet and the perception among some players that it is safe to lead or make contact with their heads while blocking or tackling [ 48].
Higher vitamin D levels may, in certain situations, paradoxically increase the pathogen burden [39] leading to a worsening of pro-inflammatory stress in the lung and thence to ALI/ARDS.
Higher vitamin D levels may, in certain situations, paradoxically increase the pathogen burden [ 39] leading to a worsening of pro-inflammatory stress in the lung and thence to ALI/ARDS.
Disseminated intravascular coagulation, the excessive activation of blood clotting, may obstruct blood flow to organs and paradoxically increase the bleeding risk.
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