Thus, decreased function of the OFC may not only impact an individual's propensity to seek rewards but may also decrease their likelihood of using a spatial navigation strategy.
Even small changes in the culture medium may not only impact the quantity of certain compounds but also the general metabolic profile of microorganisms.
As CXCR3 antagonism may not only impact on tumour cells but also on CXCR3-dependent immune mechanisms as well, working with the immunocompetent metastatic models appeared more appropriate to assess the anti-metastatic potential of this strategy.
Using both yeast one-hybrid and two-hybrid experiments, we have identified potential sources of these problems: the media preparation protocol and the source of the yeast nitrogen base may not only impact signal range but also effect whether a result appears positive or negative.
It is important to recognise that familial AD APP and presenilin mutations may not only impact Aβ production, but also the production of the other peptides produced from APP including sAPPα, sAPPβ, p3 and AICD, as well as the relative levels of full-length APP.
It turns out the recession may have not only impacted how women make ends meet, but their reproductive timelines as well.
Additionally, the model suggests that factors at different levels may not only impact on individual behavior, but may also impact on or modify each other [ 18, 29].
Oral contraceptive use may similarly only impact risk in an environment of lower estrogens.
Finally, there is the problem of endogeneity of policies, in that they may not only impact fertility and induce change, but are often a reaction to changes in fertility and an integral feature of these changes.
Of interest, mice lacking the receptor for type I IFN (IFNAR1) or IFNβ are protected against TNFα-induced lethal shock [ 25] - showing that the absence of type I IFN signaling may not only impact TNFα production, but also the outcome of the TNFα-induced inflammation.
