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They may only be identified too late – after a tragedy.
Thus, problems arising from uncertainty may only be identified late in the design process or even remain.
These unannotated methods bear of course the disadvantage that specific hits may only be identified after sequencing their respective probes.
Other organisms may require additional culture media e.g. nutritionally variant streptococcus and Campylobacter spp. Non-cultivable organisms may only be identified by molecular techniques.
Care home staff, attending GPs, and ambulance staff making difficult decisions in uncertain circumstances, particularly out of hours, may benefit from considering which of the four identified trajectories the patient or resident may be on, although for some this may only be identified retrospectively.
Although this can occur for any recessive allele, currently, it is impossible to identify individuals at risk for this rare event in advance, and these individuals may only be identified if mutation or linkage analyses are being performed or if the individual also has features of a disorder caused by imprinting.
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Specific isoforms may not only be identified as having specific tissue preferences but they may also be involved in unique functions.
The protein is so short (~50aa) that it is easily missed in bioinformatic analyses; even if the protein is more widespread, it may be that it will only be identified biochemically.
Furthermore, additional inflammatory-related or other signals may be present in peripheral blood DNA that require isolation of specific cell types to detect and other methylation change signals may only be able to be identified in the affected renal cells themselves.
However, linkage disequilibrium (LD) means these results may only be used to identify an associated region, which usually encompasses several genes.
Unbiased assessments of the viabilities of species may only be obtained by identifying and considering the most limiting processes (i.e., demography or genetics), or, preferentially, by integrating them.
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