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Thus acj6-GAL4 may not recapitulate the entire acj6 expression pattern, or may not truly express in neurons innervating the central complex.
In addition, given the possibility that mice models may not recapitulate all of the phenotypes of human bone marrow failure patients, it will also be important to examine the function of telomerase in other animal models.
This may not recapitulate normal C2C12 myoblast differentiation as previously reported [ 136].
First, target-based screening typically involves ex cellulo assays, which may not recapitulate cellular complexity.
This model may not recapitulate the whole pathogenesis of a more severe and chronic type 1 diabetes.
This suggests that LCLs may not recapitulate the epigenetic regulation of normal blood cells, which should be taken into consideration when analyzing downstream phenotypes.
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"You can plate cells on a plastic surface (as in petri dishes) and study their behavior, but this approach lacks tissue context and thus, may not fully recapitulate the in vivo situation". Fischbach-Teschl's lab has developed three-dimensional scaffolds and model systems to provide cells with this environment in order to study cancer under physiologically more relevant conditions.
It is apparent that in surgery, ontogeny may not readily recapitulate phylogeny and thus the need for a contemporary revaluation of integration within a novel educational nexus that encompasses the burgeoning matrix of biotechnological, ethical and fiduciary revolution is a critical requirement.
However, gene deletion may not completely recapitulate the effects of channel blockade, as compensatory mechanism may counterbalance the function of the absent gene-protein.
This location is not a normal niche of thyroid cancer cells and may not faithfully recapitulate the environment experienced by the cancer cells in the original tumor.
While bacterial sumoylation systems may not completely recapitulate the specificity of sumoylation in vivo, they have been repeatedly validated as a useful approach for confirming sumoylation targets [43] [46].
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