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Evidence also suggests, however, that cardiac glycosides may not inhibit cancer cell proliferation selectively and the potent inhibition of tumor growth induced by cardiac glycosides in mice xenografted with human cancer cells is probably an experimental artifact caused by their ability to selectively kill human cells versus rodent cells.
A patent upon a narrow law of nature may not inhibit future research as seriously as would a patent upon Einstein's law of relativity, but the creative value of the discovery is also considerably smaller.
The induction of bilateral eyes can be explained by the ability of Dkk1 but not Frzb (which may not inhibit all Wnts) to promote prechordal plate formation, which is essential to split the primary eye field via hedgehog signaling (Kazanskaya et al., 2000).
That may or may not inhibit a competitor like Barclays (or his old firm, Rydex) from moving into this business.
Recent clinical trials have clearly indicated that current antiplatelet strategies may not inhibit recurrent thrombotic events in selected patients and improvement is necessary.
As shown in Figure 9b, the average size of tumors in the test group is significantly smaller than in control group I and control group II (P < 0.05), and the average size of tumor in control group I was bigger than in control group II, which demonstrates that FMNP-labeled MSCs may not inhibit the growth of tumor.
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Targeting this site may therefore not inhibit the enzyme, although the possibility of long range conformational changes induced by the binding of a drug cannot be ruled out.
Furthermore, they suggest that substances which may be shown to inhibit interictal activity in various models of epilepsy may not necessarily inhibit ictal activity.
Ku's interaction with TRF2 may not only inhibit its c-NHEJ function but may additionally promote the execution of its protective telomeric functions, which are to inhibit alt-NHEJ and HDR (Bombarde et al., 2010; Sfeir and de Lange, 2012) and prevent dramatic telomere deletions in human cells, an essential function (Wang et al., 2009).
One advantage of such behavior is that surface defects such as edges and kinks may not significantly inhibit the formation of the EAK16-II nanofibers and their homogeneous distribution over the entire surface.
Thus, dependent on the cellular context, SSTRs may not only inhibit the release of neurotransmitters and hormones, but also affect cell proliferation, migration, or the formation of cellular junctions.
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CEO of Professional Science Editing for Scientists @ prosciediting.com