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First, we want to point out that this work is based solely on sequence feature analysis, so the results reported here may need experimental corroboration.
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The constructed HapMap may need further experimental validation.
Whether the other four could phosphorylate or not may need more experimental proofs.
The pathogenicity genes uncovered by Lee and co-workers were based on a high-throughput phenotype screening, and they may need further experimental validation.
Accordingly, systems-level analyses of signaling may need to integrate multiple experimental and/or computational approaches.
This tentative idealization of the experimental measurements may need to be modified, or even discarded, in the light of further experiments.
This represents one of the simplifications of the model, the validity of which may need to be determined by experimental work in the future.
However, a comprehensive experimental studies may need to be conducted based on the past research data to further explore a coherent results.
Since our data indicate that auditory orientation in crickets does not necessitate meandering walking paths as observed in other studies [34], [35], [18] the different experimental conditions may need scrutinizing.
This means that health workers belonging to experimental clusters may need to transfer patients for longer distance than they used to do.
For example, experimental tasks may need to be adapted or shortened so as not to fatigue participants (e.g., Zarrinpar et al., 2006).
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