Sentence examples for may modulate receptor from inspiring English sources

Ligand association at these interface sites may modulate receptor function.

The binding of some allosteric ligands may modulate receptor internalization and thus also fail to be detected by many functional assays and indirect signaling screens.

Steroid receptor coactivators (SRCs) may modulate estrogen receptor (ER) activity and the response to endocrine treatment in breast cancer, in part through interaction with growth factor receptor signaling pathways.

Therefore, the results presented here provide the first evidence to support the concept that the PDZ/PTB domain N-terminus and/or the PTB domain of RGS12 may modulate PDGFβ receptor signalling.

Phosphorylation sites are found in a long intracellular loop between TM3 and TM4, which may modulate the receptor activity [ 5, 6].

Recent observations have shown that the pineal hormone melatonin (MLT) may modulate oestrogen receptor (ER) expression and inhibit breast cancer cell growth.

Furthermore, based on the presented data we suggest that nucleolin may modulate ErbB receptors activities.

Based on these results we have previously suggested that nucleolin may modulate ErbB receptors activities.

Our structure provides a structural basis for the study of the pathogenesis of VHL disease and rationale for the design of novel compounds that may modulate cullin-substrate receptor interactions.

Overexpression of ApoEr2 also increased dendritic spine density, decreased levels of GluA1 and increased levels of GluA2 in primary neurons, suggesting that ApoEr2 may modulate the AMPA receptor pools at the synapse.

Ca2+ entry through the NCX may modulate the InsP3 receptor-gated channel activation, since the NCX1 isoform can associate with plasma membrane ER junctions, microdomains containing InsP3 receptors (Lencesova et al., 2004).