Sentence examples for may modulate central from inspiring English sources

Furthermore, CGRP may modulate central sensitization by increasing the discharge frequency of wide dynamic range neurons in the spinal cord, thus modulating nociceptive transmission [27].

These findings, discussed in relation to previous studies in smokers, support the notion that nicotine may modulate central executive systems and contribute to smoking behaviour.

Gene expression analysis before and after PH show that UPF2 null mice induce a transcriptional program that overlap only partially with the one induced in WT mice and suggest that the NMD pathway may modulate central components required for regeneration.

Significant negative correlations have been observed between cardiorespiratory fitness and arterial stiffness [ 7, 19], suggesting that exercise training may modulate central arterial compliance in healthy older individuals.

If the vagus nerve mediates the anti-inflammatory potential of the α2-agonists, however, central sympatholytics may modulate systemic inflammation through a mechanism mediated by the spleen [ 4].

Overall, these findings indicate that dietary phytoestrogens have a central action and may modulate energy homeostasis in part by affecting the expression of hypothalamic neuropeptides such as orexin A, MCH, and AgRP.

Our results propose that minimizing pain intensity from a peripheral source of nociception may modulate sensory hypersensitivity, but may not amend central hyperexcitability to normative levels.

The inhibition of MAGL activity, with the theoretical increase of central content of 2-AG, may modulate the activation of structures involved in pain perception and pain integration in an animal model specific for migraine.

Further studies have suggested that psychological states may modulate esophageal sensitivity in GERD patients through both peripheral and central mechanisms [ 20, 21].

ERs and aromatase are expressed in the central nervous system and local estrogen production may modulate pain and sensory perception [ 87].

Recently, it has been shown that myofascial trigger points in the upper fibres trapezius of patients with chronic WAD may be a peripheral source modulating central hyperexcitability as evidenced by a decrease in widespread mechanical hyperalgesia (pressure pain thresholds) following local anaesthetic injections [ 45].