Sentence examples for may modulate cancer from inspiring English sources

However, we can speculate that insulin may modulate cancer development through both the insulin receptor and insulin like growth factor-1 receptor (IGF-1R).

Both genetic and life-style factors contribute to the pathogenesis, and gene-environmental interactions may modulate cancer risk.

In addition, polymorphisms of genes coding for components of the Toll-like receptor signaling pathway may modulate cancer risk as single nucleotide polymorphisms of the TLR gene family.

Because pattern recognition receptors recognize a number of oncogenic infectious agents and launch an immune response against them, inherited variation in their structure may modulate cancer risk and, possibly, influence cancer progression.

In cancer cells, PHB is required for plasma membrane association of C-Raf and is indispensable for the activation of the Ras-mediated Raf-MEK-ERK signaling pathway, which may modulate cancer cell survival and migration [ 31– 31].

Thus, the difference in rs17878362 A2 allele-related cancer susceptibility in the different countries suggests that additional factors, such as environmental factors, lifestyle and other genetic modifiers, may modulate cancer susceptibility associated with this allele.

High serum glucose levels may modulate cancer-related processes.

Extensive evidence has suggested that risk factors of cancer development may also modulate cancer clinical outcome.

Like PHD, histone methyl demethylases are also dependent on iron and 2-OG, and therefore mitochondrial cholesterol loading may further modulate cancer progression by the regulation of histone lysine demethylases via limitation of cytosolic 2-OG levels, which deserves further investigation.

IRP1- and IRP2-overexpressing tumours exhibited distinct gene-expression profiles, suggesting that IRPs may differentially modulate cancer growth by mechanisms independent of their function as IRE-binding proteins.

Secondly, lacking the original data of the included studies limited our study to further evaluate the potential interactions, since gene-environment and gene-gene interactions and even different polymorphic loci of the same gene may also modulate cancer risk.