Sentence examples for may modulate aggregation from inspiring English sources

This indicates that copper may modulate aggregation by influencing proximal mutant huntingtin structural changes in the cascade from monomer to oligomer and microscopic aggregate.

Third, phosphorylation of TDP-43 may modulate aggregation and toxicity of the protein [ 26, 126].

Even in the acid unfolded state it appears that specifically structured species presenting aggregation-prone regions are required for amyloid formation, whilst other transiently structured regions may modulate aggregation by sequestering sequences with high amyloid forming potential.

As aSyn misfolds and aggregates in PD, and DJ-1 displays chaperone-like functions, we hypothesized that DJ-1 may modulate aSyn aggregation.

We speculate that other membrane-associated molecules may modulate CEACAM6 aggregation and signal transduction, although this aspect of CEACAM6 biology requires further study.

The lead compounds -8a and -14 were able to modulate aggregation of α-synuclein protein efficiently.

Hsp70 proteins and their co-chaperones have been shown to modulate aggregation in models of neurodegenerative diseases.

This suggests that other (likely olfactory) components may modulate the full aggregation phenotype, but that 9-tricosene can function as an aggregation molecule.

This N-terminal conformational change may modulate the propensity of PrP aggregation since this region influences the amount of secondary structure in the remainder of the molecule [ 49].

Combined with ThT fluorescence, SDS-PAGE, and EM experiment, we propose that geniposide may modulate the folding pathway of aggregation-prone polypeptides and thereby prevents their assembly into toxic aggregation products.

The degree of CNT-bacteria aggregation was influenced by CNT functionalization and length may modulate the toxic effect on the bacteria.