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In contrast, mutated ERs may moderately perturb the epigenetic network, resulting in global gene deregulation.
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Alternatively, the robustness of transcription factor regulatory networks may mean that the level of expression of genes expressed for MC terminal differentiation are only moderately perturbed by the complete absence of CEH-19 activity.
Note, however, that CycA and CycE (moderately perturbed at a distance of five steps from NF-κBn) are less perturbed in the full system.
Among the other metal ions examined in the study, Cd2+ moderately perturbed the emission of 1 under similar conditions.
The species directly influenced by NF-κBn (CycD) is only weakly perturbed, while species as far as five steps away in the network (i.e., CycA, CycE) are moderately perturbed.
These mechanisms may explain how LysM2 of Ecp6 may perturb chitin-triggered immune signaling.
These new conformations may easily perturb, for example, protein-DNA binding and thereby induce changes in cellular transcription and replication.
This result suggests that overexpression of eat-6 may also perturb ACh synaptic transmission at the locomotory NMJs.
We were interested whether the gene trap mutation may also perturb meiosis and in particular meiotic chromosome condensation.
Here, we define pVDCs to include compounds that may directly perturb processes fundamental to vascular development.
During development, alterations in the ratio of neurons to glia may severely perturb neuronal function.
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