Sentence examples for may mediate uptake from inspiring English sources
These results together with the lack of intracellular colocalization with CtxB (below) suggest that recognition of different glycolipids (in this case GD1a vs. GM1), perhaps in combination with membrane proteins, may mediate uptake into distinct intracellular trafficking routes, as suggested by Lencer and colleagues [92].
The genes surrounding the two lyase genes are also duplicates, and encode periplasmic substrate-binding proteins (Pcar_0492, Pcar_0468) and multitransmembrane proteins (Pcar_0490, Pcar_0466) that may mediate uptake of ethanolamine or choline, as well as proteins of unknown function (Pcar_0493, Pcar_0469) of which a third paralog (Pcar_1023) is encoded next to one of the two ammonium transporters.
Since phenylalanine residues elsewhere in the protein have been implicated in ligand binding, we explored the structure of this N-terminal region to investigate structural determinants near the cytoplasmic opening that may mediate drug uptake.
These data suggest that SynK may mediate K+ uptake when expressed in E. coli.
It is possible that the ZMK1 channel, as an orthologue of the Arabidopsis AKT1 channel (Geiger et al. 2009), may mediate the uptake of K+ under K+-limiting conditions.
Here we discuss how competence induced pili, either by pilus retraction or by a transient pilus-related opening in the cell wall, may mediate DNA uptake in S. pneumoniae.
AtOPT6 can mediate uptake of glutathione derivatives and metal complexes, indicating that it may also be involved in redox homeostasis [ 87].
The reason for this variation is not known, but it is possible that cones differentially express the nucleolin cell-surface protein known to mediate uptake of the nanoparticles [12]; alternatively, heterogeneity in the response to the injection insult may affect NMP expression/uptake.
Here we show that in different experimental models, PrPC is able to mediate uptake of α-Syn amyloid fibrils in contrast to models where PrPC expression is ablated.
The LDLR itself may mediate second signaling by mediating the uptake and degradation of LDL particles, which in turn may release molecules with signaling properties [16], [17].
Fourthly, α-folate receptor (α-FR) mediated uptake may contribute to the activity of some antifolates, particularly BGC9331 (Theti and Jackman, 2004).
