Sentence examples for may mediate progression from inspiring English sources

It has also been proposed that statins may mediate progression of structural disease in ADPKD.

A better understanding of neuroinflammation could open therapeutic avenues for abrogation of secondary cell death and behavioral symptoms that may mediate the progression of TBI.

Recently, data suggesting mechanisms by which HMGA1 may mediate cancer progression have begun to emerge.

Specifically, in endomitosis and polyploidisation development, ROS may mediate the progression of G1 S phase by regulating G1 cyclin gene expression, and NOX inhibitors can downregulate the effects of cyclins D3 and E on MK polyploidisation.

Based on these findings, which strongly indicate that MEK5/Erk5 signaling may mediate cancer progression to an aggressive phenotype, we further explored the involvement of MEK5/Erk5 signaling in resistance to apoptosis as well as EMT.

Taken together, PI3K may mediate G1-S progression by cyclin D1 induction, however p110β-isoform is unlikely to directly regulate cyclin D1.

In combination, these data suggest that myeloma cells alter the function of MSC through changes in gene expression profiles, while concurrently providing a mechanism whereby MSC may mediate MM disease progression.

These results indicate that PVT1 may mediate the development and progression of diabetic nephropathy through mechanisms involving ECM accumulation.

The CCL20-CCR6 axis may mediate the growth and progression of HCC through phosphorylation of MAPK [ 20, 21] and is associated with poor prognosis after resection [ 22, 23].

These extranuclear effects of PR may mediate mammary hyperplasia and tumor progression in the outgrowths derived from the CDβ cells.

The end-products of COX-2 activity are prostaglandins and thromboxanes which may mediate these changes in cancer cell progression.