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Preliminary analysis suggested RACK1 may mediate multiple hormone responses and developmental processes in Arabidopsis [ 15].
Interestingly, lin-35 and spr-1 display a synthetic genetic interaction affecting gonadogenesis (Bender et al. 2007), suggesting that CoREST may mediate multiple functions needed for optimal germline development and reproduction.
These data show that flagellar motility plays a role in inducing a specific host immune response that is independent of its later role in migration into the light-organ crypts (Brennan et al., 2013), suggesting that biosynthesis of the flagellum, and its subsequent functions, may mediate multiple aspects of symbiotic initiation.
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These findings support the idea that mast cell histamine may mediate pain in multiple pelvic pain syndromes.
PTH may mediate the induction of multiple myeloma.
Second, Hox genes participate in diverse cell fate determination and reprogramming [ 52, 53], which suggests that Hox-related lncRNAs may mediate genome modification at multiple loci.
According to the previous study [ 5], it was hypothesized that elevated PTH may mediate the induction of multiple myeloma (MM) through the downstream biologic effects of interleukin 6 (IL-6).
In short, multiple factors may mediate tangential expansion and contribute to the pattern specificity of folds.
It is possible that the multiple IRES sequences may mediate the homologous recombination and lead to the instability of the recombinants.
LRRK2 additionally contains multiple repeat domains that may mediate protein protein interactions, including N-terminal LRRK2-specific, ankyrin and leucine-rich and C-terminal WD40 repeat domains.
Notably, these preconditioning-induced ROS may mediate protein kinase C (PKC) activity and, via multiple steps, inhibit the opening of mPTP [ 2, 7].
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