Sentence examples for may mediate genome from inspiring English sources

Second, Hox genes participate in diverse cell fate determination and reprogramming [ 52, 53], which suggests that Hox-related lncRNAs may mediate genome modification at multiple loci.

Genome rearrangements may occur via homologous recombination of repeat elements in the bacterial genomes [ 35, 36]. A. actinomycetemcomitans genomes contain diverse repeat elements that may mediate genome rearrangement.

Hence the occurrence of repeated sequences may mediate genome, epigenome and transcriptome interactions, such as chromosomal rearrangements [ 5- 7], centromere [ 8] and telomere [ 9] function, and chromatin remodelling and gene silencing mediated by repeat-induced small RNAs [ 10- 15].

However, gene transposition or translocation may occur more frequently than chromosomal translocation, simply because there are more genes than chromosomes in the genome and transposons may mediate gene transfer.

Furthermore, based on the variable functions of the regulating genes, intragenic L1s may mediate several cellular phenotypes and are associated with the genome-wide gene expression observed in several diseases.

Next, we addressed the question of whether rDNA stability-mediated genome integrity may be affected during chronological aging, especially if whole chromosome aneuploidy may limit CLS.

Thus, TERRA may mediate several crucial functions at the telomeres, a region of the genome that had been considered to be transcriptionally silent.

TEs promote chromosomal rearrangements more efficiently than other cellular processes, and TEs have been proposed as drivers of plant pathogen genome evolution due to the fact that they may mediate chromosomal rearrangements by ectopic recombination (Schmidt and Panstruga 2011).

Transposable elements have accumulated in mating-type chromosomal regions and were also associated across the genome with gene clusters of small secreted proteins, which may mediate host interactions.

Recent evidence has suggested that in addition to producing RNA transcripts, chromatin-assembled RNA polymerase III complexes may mediate additional nuclear functions that include chromatin boundary, nucleosome phasing, and general genome organization activities.

Insulin resistance may mediate the association of hyperuricemia with GKRP, as identified by a genome-wide association analysis [ 27].