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It is possible that the binding of PIPs such as PI(3 P may mediate entry of NaD1 into cells.
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ORF2 peptide-binding experiments suggested that the C-terminal region of ORF2 may mediate virus entry by binding to heat shock cognate protein 70 (HSC70) on the cell surface.
Here we focus on evidence that DT40 cells express functional IP3R in the PM and suggest that these may mediate Ca2+ entry via the non-SOCE pathway.
A polymeric IgA against the EBV antigen(s) may mediate EBV entry into pharyngeal epithelial cells via an endocytic route [17]– [17].
As the Cx induced [Ca2+]i increase is sensitive to mibefradil, a CatSper blocker, this channel may mediate the Cx-induced Ca2+ entry leading to the AR.
In olfactory cilia, ANO2 may mediate efflux of chloride ions following calcium entry through cyclic nucleotide-gated channels, thereby amplifying the magnitude of the depolarizing signal in response to odorants [21], [23].
Some experts believe that they may mediate the effects of other cannabinoids.
Both moieties may mediate atherogenicity.
Higher BMI may mediate this association.
High-glucose environment may mediate these findings.
Viral glycoproteins mediate entry by pH-activated or receptor-engaged activation and exist in metastable pre-fusogenic states that may be stabilized by directed rational design.
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