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Remarkably, the purified 3′ processing complex contains ∼85 proteins, including known and new core 3′ processing factors and over 50 proteins that may mediate crosstalk with other processes.
Phosphoinositide metabolism may mediate crosstalk between P2X and P2Y family members in neurons.
Flavonoids are inhibitors of auxin transport and thus may mediate crosstalk between cytokinin and auxin action.
Additionally, the human pre-mRNA 3′-processing containscontapproximatelyately 85 proteins, including core 3′-processing factors and over 50 proteins that may mediate crosstalk between pre-mRNA 3′-processing and other nuclear events.
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Thus, from the above analysis, CAV1 may mediate the crosstalk between liver metabolism and cell death signaling pathway and is a potential biomarker in clinical practice.
An ABA-responsive NAC transcription factor VND-INTERACTING2 (VNI2), whose expression shows a leaf aging or leaf longevity-dependent expression pattern, may mediate the crosstalk between the salt stress response and the leaf aging process [ 9].
This confirms the idea that E2F CREs are involved in the interaction of the NO3- response with other signals such as hormones and may be mediating crosstalk between these signals.
TYROBP is involved in signaling events that mediate crosstalk between dendritic cells and natural killer cells.
Recent data also indicate that upregulation of the ErbB receptors may mediate endocrine resistance, due to crosstalk between the ErbB and estrogen receptor (ER) signal transduction pathways.
Regulatory T cells (Tregs) may also be involved in mediating crosstalk at mucosal sites.
Both moieties may mediate atherogenicity.
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