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In E. tarda, TCSs may mediate adaptive responses to a broad range of environmental stimuli, including phosphate/Mg2+ limitation (Pho), anaerobic condition (Cit and Arc), heavy metal overload (Cus), osmosis change (EnvZ/OmpR), and motility/chemotaxis (Che), etc.
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Biogenic amines signaling could allow the worm to adapt to fast changes in the environment when peptide transcriptional pathways may mediate slower adaptive changes.
We conclude that we have identified a novel transcriptional signature that may mediate the adaptive response to changes in milking frequency.
However, their potency to mediate adaptive immune response was not affected.
Two-component systems are known to mediate adaptive responses to various environmental signals [32].
Alternatively, neo-functionalization could involve adaptive differentiation of both copies (to avoid functional overlap), that would mediate adaptive evolution of both copies.
This adaptive effect may mediate the health-beneficial effect and play an important role in protecting against chronic non-communicable diseases which are associated with low-grade inflammation [ 21].
Adaptive, stress-protective, responses may mediate the lifespan extension associated with low levels of ROS (Doonan et al., 2008; Yang & Hekimi, 2010; Zarse et al., 2012; Martins et al., 2014).
As such, autophagy is initially an adaptive response to ensure survival but beyond a certain threshold may mediate a form of non-caspase-mediated cell death.
Taken together, our findings point to TrkA as a candidate oncogene in MM and support a model in which the NGF-TrkA-MAPK pathway may mediate a trade-off between neoplastic transformation and adaptive anti-proliferative response.
While the underlying reasons for this are unclear, the intact adaptive responses (Dorhoi et al., 2010) may mediate protection due to successful vaccination of these patients in endemic areas.
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CEO of Professional Science Editing for Scientists @ prosciediting.com