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Our previous work on breast cancer and the current data from lung cancer suggest that USP33 may mediate Slit signaling in different cancer cells through different mechanisms.
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Our previous data have shown that one of the Robo-interacting proteins that mediate Slit-Robo signaling is ubiquitin specific protease 33 (USP33), also known as von Hippel-Lindau (VHL -interacting deubiqutinating enzymes 1, (VHL -interactingadeubiqutinatinga, b).
EN2 secretion may mediate anti-viral changes in the stroma.
Alternatively, periplasmic proteases may mediate proteostasis of these amyloidogenic proteins.
Some of these channels may mediate mechanosensory responses.
Glutamatergic dysfunction may mediate some of these symptoms.
These specific regions may mediate the, specific effects of acupuncture.
Roberts, D.D. et al. Thrombospondin binds falciparum malaria parasitized erythrocytes and may mediate cytoadherence.
HMGB1/RAGE signaling may mediate NSC differentiation and promote neuronal recovery after SCI.
Thus, virus-specific T cell responses may mediate protection under such circumstances10,11.
Interestingly, endocytosis was the unique function with top enrichment score, suggesting endocytosis may mediate LSEC dedifferentiation.
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