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Using Affymetrix annotation tables [ 26], we identified all probesets labeled as NSMPs that were not characterized with "cross hyb," indicating the probeset may match to another gene.
Sometimes a repetitive sequence may match to thousands of places in the human genome and extending partial matches each time may be slow.
However, due to their short length, cloned small RNAs may match to many genome regions that can potentially fold into hairpin structures which may not be unique to miRNAs.
Even more pronounced than in classical bottom-up proteomic approaches (Nesvizhskii, 2010), one spectrum can not only match to several peptides occurring in multiple proteins of the same organism, but may match to proteins in different organisms.
In parts A and B, the number of EST contigs matched was out of a total of 6,430 unique contigs matched by 17-base signatures or 5,831 by 20-base signatures; signatures from different filter categories may match to the same contig (see Additional file 1A– 1B and Table 3 for details).
A limitation of genome wide gene expression analysis using DGE is that it is not possible to evaluate the expression of genes that do not contain a NlaIII restriction site and in some cases there is ambiguity regarding the tag-gene matches as a single tag may match to two or more genes.
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Such created library entries for each chemical entity may match well to an entry in the library, or as an unknown to be added to the library and to be further identified with more studies.
Some subreads may match perfectly to different parts within the genome (so-called multireads).
For example, a framework that documents desired characteristics of a service, based on the published literature, may match imperfectly to qualitative data from stakeholders.
We assess patients for injuries, offer medications to reduce the risk of sexually transmitted infections and collect forensic evidence that may match an assailant to the crime.
Populations may match their phenotype to an environment via phenotypic plasticity rather than genetic adaptation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com