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The finding in the present study demonstrated that acidic intra-tumour environment may markedly perturb the tumour cell proliferation and tumour growth.
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The three-dimensional structure of probe (1) in DPC micelles essentially resembles that reported for polymyxin B, indicating that introduction of the dansyl group does not markedly perturb the native structure.
EnMT is markedly perturbed in mice lacking Tbx20 (Cai et al., 2011).
Endocrine cell differentiation is markedly perturbed in mice lacking Insm1 (Gierl et al., 2006).
Unexpectedly, we found that neurogenic differentiation was markedly perturbed by functional knockdown of MYC.
In patients with polymyositis with relapsing disease, markedly perturbed T cell repertoires were seen.
When mDia1 was depleted by shRNA, the lateral periodicity in the distribution of α-actinin was markedly perturbed.
Vaccination had no global effect on neurovascular coupling but markedly perturbed neural reactivity within substantia nigra during low-level visual stimulation.
Moreover, blood serum cholesterol decreases in the HDL fraction while it increases in LDLs, suggesting that during proliferative processes cholesterol fluxes between tissues and serum lipoproteins are markedly perturbed.
These changes may markedly alter the pharmacodynamics of nifedipine.
These mechanisms may explain how LysM2 of Ecp6 may perturb chitin-triggered immune signaling.
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CEO of Professional Science Editing for Scientists @ prosciediting.com