Sentence examples for may markedly impair from inspiring English sources

The disease is associated with serious complications of the eyes, kidneys, heart and blood vessels, and other organ systems, which may markedly impair quality of life and shorten the patient's lifespan.

A limitation of the study by Shorr and colleagues is that focusing on zymogen protein C levels may ignore the fact that, in patients with severe sepsis, protein C activation may be markedly impaired.

These findings provide additional evidence of a dissociation between macro- and microcirculations, as reported for the sublingual area in human sepsis [ 13, 32] and suggest that, even after restoration of adequate global hemodynamics, cerebral perfusion may still remain markedly impaired as a result of microcirculatory alterations.

The deficiency blocks proliferation of Treg cells and homeostatic expansion, but it does not markedly impair their survival.

It makes oral food intake difficult and can markedly impair the quality of life.

Moreover, we demonstrate that these mutations markedly impair ion channel activity.

The other drugs did not markedly impair the growth of empty vector transformants.

Untreated, visual hallucinations in dementia with Lewy bodies can markedly impair quality of life and significantly increase caregiver distress.

A recent systematic review found that these depressive symptoms markedly impair their health-related quality of life.

On the other hand, because hypoxic pulmonary vasoconstriction is markedly impaired by lung and systemic inflammation [ 3], increase in venous mixed oxygen saturation (SvO2) may improve arterial oxygenation if pulmonary blood flow does not increase in non aerated lung regions.

The quality of your life would be markedly impaired.