Sentence examples for may markedly alter from inspiring English sources
These changes may markedly alter the pharmacodynamics of nifedipine.
Therefore, host cells, mainly in proximity to tumor cells, may markedly alter tumor growth and invasiveness.
Recent evidence suggests that, as with HER2 and EGFR, the HER4 protein can be enzymatically cleaved, which may markedly alter the function of the intracellular domain of the receptor.
Although everyday symptoms in these patients are dominated by epistaxis that may markedly alter their quality of life, more severe manifestations of the disease are due to the consequences of pulmonary arteriovenous malformations (PAVMs) and, less often, to liver, brain, or gastrointestinal tract involvement [ 1].
The present data indicate that mesna depletes circulating cyst e)ine and may thereby markedly alter the sulfhydryl status of cells in vivo although the drug itself is not taken up by most cells.
Whilst epithelial cell Na/K-ATPase activity for example may be markedly altered by such factors the myofibroblasts may also be considered responsive elements.
This study suggests that important stretch responses of collagen made possible by collagen crimping may be markedly altered by morphologic changes during aging/degeneration and may contribute to the early tissue changes involved in annular tears.
Although proteoglycan loss has long been acknowledged to be an important part of disc aging and degeneration, the work presented here suggests that important stretch responses of collagen made possible by collagen crimping may be markedly altered by morphologic changes in disc architecture during aging/degeneration; such changes may contribute to the early tissue changes involved in annular tears.
Patients with DPD deficiency may demonstrate a markedly altered pharmacokinetic profile with significant reduction in the plasma levels of 5FU metabolites.
Moreover, specific physical activities can markedly alter its structure in precise ways.
An Ohio court ruling on Thursday could markedly alter negotiations between Major League Baseball draft picks and their teams if it withstands appeal.
