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We demonstrate that gut specific antigen presentation is sufficient to induce CD8+ Tregs in vivo which may maintain intestinal homeostasis by down-modulating effector functions of T cells.
These results suggested that 1,25(OH)2D3 may maintain intestinal epithelial integrity by decreasing paracellular permeability.
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147 Furthermore miR-10 directly targets IL-12/23p40 to limit Th17 driven inflammation and the expression of this miRNA may be regulated in order to maintain intestinal homoeostasis.
We demonstrate that targeted manipulation of intestinal microbiota through FMT may elicit microecological and immunological mechanisms to maintain intestinal homeostasis and protect the patient.
Our studies, thus, provide insight into how microbiota metabolites regulate Th1 cell functions to maintain intestinal homeostasis.
The interaction between the microbiota and the intestinal mucosa through TLRs is required to maintain intestinal homeostasis.
Wnt signals predominate at the intestinal crypt-base and maintain intestinal stem cell biology.
Glutamine is essential to maintain intestinal integrity and function, sustain immunologic response, and maintain antioxidative balance.
The expression of the operon can transform redundant glucose into cellulose to maintain intestinal peristalsis.
Currently, how to maintain intestinal health is a major challenge in medicine.
In our PI-IBS model, by 56 days PI, T. spiralis was completely absent from the intestinal mucosa but IL-17 still persisted, suggesting that increased IL-17 in the duodenum and ileum may be vital for maintaining intestinal low-grade inflammation.
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