Sentence examples for may mainly mediate from inspiring English sources

On the other hand, in the absence of Siz2, more Rpb1 may be available for Siz1, which may mainly mediate mono- or oligo-sumoylation of Rpb1.

Since ABC transporter family utilize the energy of ATP hydrolysis to transport various small molecules across cellular membranes, it seems that ABC transporters may mainly mediate the efflux of erythromycin rather than import molecules associated with erythromycin synthesis.

It is noteworthy that changes in SBRS regulation may be mainly mediated by parasympathetic tone, an idea also set forth by Tank et al[35].

Combined with the observation that adult germ cells proliferate through a cyclin D1-independent pathway, our results suggest that the effect of miR-383 on pRb phosphorylation in the human testis may be mainly mediated by the activated CDK4 expression.

Whereas only a few of the environmental factors that cause disease susceptibility have been shown to promote mutation in DNA sequence, emerging evidence suggests that environmental influences may mainly be mediated by epigenetics, i.e., the processes that lead to changes in gene expression without a change in the DNA sequence [1], [2], [3].

D2L receptors mainly mediate post-synaptic signaling.

When participating in cellular processes, sRNAs mainly mediate mRNA degradation or translational repression.

Our findings suggest that this SR may have been attributable to an immune-mediated antitumor response, mainly mediated by CD4+ T cells.

Collectively, these data suggest that the Ub mediated FOXO3 protein degradation is mainly mediated through βTrCP1 but may not be regulated by βTrCP2.

Cellular senescence may result from a variety of stresses, mainly mediated by two tumor-suppressor pathways involving p53 and p16-pRB.

Additionally, as deferoxamine has also been shown to have immunosuppressive effects on T cells [54], which is mainly mediated through iron sequestering, yersiniabactin may also have immunosuppressive qualities.