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A greater level of variability can be tolerated due to the RPM detection process but when it is too great it may lower sensitivity.
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Malnutrition may lower the sensitivity of the IGRA [ 14].
However, formation of ammonia in exposed urine causes degradation of DNA and may lower the sensitivity of the tests.
Multiple testing correction techniques are known as conservative approaches and applying them may lower the sensitivity of pathway discovery.
Technical challenges in relation to DWI may lower tumour sensitivity due to anatomical distortion, inadequate suppression of benign prostate tissue and suboptimal ADC map windowing.
36, 48 Thus, elimination of somatic symptoms from instruments screening for depression among the Baganda may lower the sensitivity of the screening instrument.
Therefore, the observed difference may be partially due to lower sensitivity of the antibody detection of cytoplasmic endogenous Dystrophin compared to the higher sensitivity of GFP detection.
Preclinical evidence suggests that high levels of TS may indicate lowered sensitivity to antifolates [ 24, 25].
This may lower the overall sensitivity and specificity of prediction when considering the whole cohort.
Because of the extreme genetic instability of breast carcinoma cells, deficient expression of the marker gene in micrometastatic tumour cells may lower the actual sensitivity as compared with immunocytochemistry.
However, heterogeneity of the non-polio AFP rate may imply effectively lowered sensitivity if low non-polio AFP rates correlate with the places most likely to incur polio cases.
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