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We study whether random transfers may locally improve upon the egalitarian outcome.
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Strategies designed to induce the UPR locally may therefore improve the therapeutic benefits afforded by readthrough therapy.
Furthermore, the product surface temperature may locally exceed 100 °C.
With the available data, there are various options to intensify treatment for patients with locally advanced head and neck tumours: modern radiotherapy techniques provide tools for relative dose escalation within the tumour, particle therapy may further improve local control by increased biological effectiveness, and induction chemotherapy improves long-term survival in these patients.
Overall, neoadjuvant chemoradiotherapy for locally advanced OSCC may improve histopathological response and R0 resection rates.
Wider experience and increased use of chemoradiotherapy in the UK since 2002 may further improve survival for women with locally advanced cervical cancer.
In summary, there is a possibility that induction chemotherapy may improve survival in locally advanced HNSCC in combination with CRT as suggested by lower level evidence.
Consequently, multidimensional ecologic data may help us improve public health locally and globally.
With regards to data demonstrating that treatment of tumor-bearing mice with P2Et fraction results in significant reduction in serum IL-6, we hypothesize that locally produced IL-6 may improve apoptosis mechanisms and are consumed immediately by tumor cells during its death process thus acting in an autocrine fashion as previously discussed.
Neoadjuvant (induction) chemotherapy before radiotherapy may significantly reduce the risk of locoregional recurrence and distant metastases and may improve disease specific survival in locally advanced NPC [ 11].
Consequently, by using established EPE [ 32, 33] as the histopathological criterion for clinically significant, locally advanced disease, MRI accuracy may improve.
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