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This suggests that in 293 cells, Maf1 may localize correctly to the nucleus after MMS treatment but that another signal, lost in 293 cells, is required for Maf1 activation by DNA damage.
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Red circles point out the first impact that we were not able to localize correctly.
This phenotype often results from a failure to localize correctly the actin polymerization nucleation center.
This novel activity of CD152 adds to the already significant role of CD152 in controlling peripheral immune responses by allowing T cells to localize correctly during infection.
Both mutants localize correctly at the plasma membrane.
The kinase domain alone is active, but does not localize correctly, while the RCC1 domain localizes correctly and can be phosphorylated by Nek8.
All markers localize correctly, labeling the Spitzenkörper and sites of polar exocytosis.
All markers localize correctly, proven by live cell imaging and co-staining and pharmaceutical studies.
In the absence of CD81, the activated B-cell receptor fails to localize correctly to lipid raft microdomains and fails to induce sustained signalling [ 44, 45].
In the absence of functional dystrophin protein, the DAPC fails to localize correctly at the sarcolemma and its function is therefore compromised.
CD4+ DCs migrate strongly to 7α,25-OHC and the CD4+ DCs remaining in the spleen of EBI2-deficient mice fail to localize correctly in MZ bridging channels.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com