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These difficulties and a price of $29,000 may limit widespread use of the iBOT.
Unfortunately, combining the results of multiple models incurs some inconvenience for practical use, and the large size of the file containing the trained parameters for Model 2 (over 1 Gb) may limit widespread use.
An admittedly substantial side-effect profile may limit widespread use of FOLFIRINOX and, despite representing potentially significant advances over the prior collective experience, neither regimen is curative.
However, lack of information on reliability, validity and sensitivity for patients with DD, together with lengthy completion time [ 120] and the need for cumbersome equipment, may limit widespread use.
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In terms of consumer confidence, unlike other wastes (e.g. biosolids and construction/demolition waste) the mineral quarry wastes can be expected to be free of potentially toxic elements, however, the production costs of compost mineral waste mixtures and subsequent transport costs may limit its widespread use.
Conventional replication-competent vaccinia vectors are considered to be effective in mucosal vaccination but their safety issues may limit their widespread use in humans [32].
Surfactant instillation by flexible feeding tube has several technical difficulties that may limit its widespread application.
However, the concerns over safety may limit the widespread deployment of nanoremediation.
However, there are several barriers that may limit more widespread use of rHuEPO.
Finally, the high cost of HbA1c test may limit its widespread use in China.
11 The need to specifically tailor foldamers towards the target protein, however, may limit the widespread use of this technology.
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